After his cattle rancher boss dies, right-hand man Pike is given the job of returning $86,000 to some families who live across the border in Senora, Mexico. Honest Pike is joined on the trip through the wilderness by a dishonest gambler named Tyree

A reporter and a blind retired journalist try to solve a series of murders. The crimes are connected to experiments by a pharmaceutical company in secret research. The two end up becoming targets of the killer.

Roberto, a shy law student in Rome, meets Bruno, a forty-year-old exuberant, capricious man, who takes him for a drive through the Roman and Tuscany countries in the summer of 1962. They will spend two days together, meet both Roberto’s and Bruno’s family. The time Roberto spends with Bruno is a hilarious, but sometimes emotionally merciless accelerated maturization process. While Bruno’s easy going “l’usage du monde” and societal success attract Roberto’s great admiration, he also slowly realizes Bruno’s hollowness, superficiality and unhappiness.