When two brothers, Josh and Mike, go to a small southern town for a vacation, they find most of the residents either dead or missing. When Mike himself goes missing, Josh teams up with the local sheriff and an attractive school teacher to find him until Josh discovers that the whole town and most of it’s people have been infected by a form of toxic waste, and they have all turned into toxic vampires whom prowl the streets at night for human blood!

An ancient intergalactic warrior arrives on Earth to put a stop to a demonic child’s plot to reproduce Satan’s next generation of evil.

Intent on seeing the Cahulawassee River before it’s turned into one huge lake, outdoor fanatic Lewis Medlock takes his friends on a river-rafting trip they’ll never forget into the dangerous American back-country.