Ever since her parents left her as a baby, little Annie has led a hard-knock life with her calculating foster mother, Miss Hannigan. However, all that changes when hard-nosed billionaire and mayoral candidate Will Stacks takes her in on the recommendation of his advisers. Stacks believes that he’s Annie’s guardian angel, but the plucky youngster’s confidence and sunny outlook may mean that Annie will save Will instead.

In an effort to tap into his original talent, a wheelchair-bound author moves to a rural town, where he befriends a single mother and her three kids, who help reignite his passion for writing.