A 17-year old Missouri teen named Veronica discovers she has gotten pregnant, a development that threatens to end her dreams of matriculating at an Ivy League college, and the career that could follow.

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CDC researcher Abby Arcane investigates what seems to be a deadly swamp-born virus in a small town in Louisiana but she soon discovers that the swamp holds mystical and terrifying secrets. When unexplainable and chilling horrors emerge from the murky marsh, no one is safe.

A gunslinger, a vengeful ex-slave, and a runaway board a midnight train to Atlanta. They discover that the train is haunted by a sinister force, and must fight to survive the night.