In 1926, Newt Scamander arrives at the Magical Congress of the United States of America with a magically expanded briefcase, which houses a number of dangerous creatures and their habitats. When the creatures escape from the briefcase, it sends the American wizarding authorities after Newt, and threatens to strain even further the state of magical and non-magical relations.

In 1957, a son and mother flee the East and an abusive boyfriend to find a new life, and end up in Seattle, where the mother meets a polite garage mechanic. The boy continually gets into trouble by hanging out with the wrong crowd. The mom marries the mechanic, but they soon find out that he’s an abusive and unreasoning alcoholic, and they struggle to maintain hope in an impossible situation as the boy grows up with plans to escape the small town by any means possible. Based on a true story by Tobias Wolff.